Mechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein Processing

TitleMechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein Processing
Publication TypeJournal Article
Year of Publication2013
AuthorsLiu X., Wong H., Scearce-Levie K., Watts R.J, Coraggio M., Shin Y.G, Peng K., Wildsmith K.R, Atwal J.K, Mango J., Schauer S.P, Regal K., Hunt K.W, Thomas A.A, Siu M., Lyssikatos J., Deshmukh G., Hop C.ECA
JournalDrug Metabolism and Disposition
Volume41
Issue7
Pagination1319 - 1328
Date Published07/2013
URLhttp://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.112.050864
DOI10.1124/dmd.112.050864
Short TitleDrug Metabolism and Disposition