Granting Agency | Subject | Principal Investigator | Co-Investigator(s) |
Canadian Institutes of Health Research (CIHR) | DRUG SAFETY and EFFECTIVENESS NETWORK (DSEN) SEARCH (active Surveillance and Evaluation of Adverse Reactions in Canadian Healthcare) & PREVENT (Pharmacogenomics of Adverse Reaction EVEnts) National Team | Colin Ross | Abby Collier, Bruce Carleton, Amit Bhavsar, M Rogers, Rod Rassekh, Michael Rieder, Shinya Ito |
Office of the Vice President Research and Innovation, UBC | Research Support for the Pharmaceutical Sciences Analytical Suite | Abby Collier | Judy Wong |
Faculty of Pharm Sci Office of Associate Dean Research | Improved PBPK Scaling from Preclinical Models to First-in-Human Trials. Funds for Re-opening after COVID | Abby Collier | |
National Science and Engineering Council of Canada (NSERC) | A UHPLC for steroid analysis Research Tools and Infrastructure competition | Abby Collier, Kiran Soma | Kiran Soma |
CIHR | Validation and commercialization of an innovative analgesic for chronic pain Project Grant | Shyh-Dar Li | Abby Collier, Brian Cairns, Jim Kim, Amanda Malone, Ernie Puil |
Genentech Ltd | Improved PBPK Scaling from Preclinical Models to First-in-Human Trials | Abby Collier | |
CIHR | DRUG SAFETY and EFFECTIVENESS NETWORK (DSEN) SEARCH (active Surveillance and Evaluation of Adverse Reactions in Canadian Healthcare) & PREVENT (Pharmacogenomics of Adverse Reaction EVEnts) National Team | Colin Ross | Abby, Collier, Bruce Carleton, Ursula Amstutz, Amit Bhavsar, Kerry Goralski, Greg Guilcher, Shinya Ito, Denis Lebel, Rod Rassekh, Michael Rieder, Geert t’Jong, Regis Vaillancourt |
NSERC | Post Translational Mechanisms of UGT Function Discovery Grant | Abby Collier | |
CIHR | Correcting monogenic skin diseases in situ: Assessing the potential of topically applicable gene therapies | Sarah Hedtrich | Shyh-Dar Li, Colin Ross |
Canada Foundation for Innovation and BC Knowledge Development Fund | Complex human-based organ (disease) models for basic and preclinical research with a focus on human epithelia | Sarah Hedtrich | |
NSERC | Development of complex human-based organ models | Sarah Hedtrich | |
BREATHE The Lung Foundation | The Skin-Lung Crosstalk: Approaching the Atopic March | Sarah Hedtrich | Tillie Hackett |
CIHR | Targeting TSLP - Novel anti-inflammatory compounds for the treatment and prevention of atopic diseases | Sarah Hedtrich | Brent Page, David Granville |
Mitacs | Rational Nanoparticle Design for Efficient Transmucosal Gene Delivery | Sarah Hedtrich & James Feng (Math, UBC) | |
Federal Ministry of Education and Research, Germany | ImmuSkin - Autologous approach for the development of an immunocompetent skin model | Sarah Hedtrich & Burkhard Kleuser (U Potsdam, Germany) | |
National Centres of Excellence | Nanoparticle formulations for anti-inflammatory IDR peptides | Bob Hancock | Sarah Hedtrich, Andrew Halayko, Neelofer Mookherjee, Azita Haddadi |
CIHR Catalyst Grant | Skin Investigation Network of Canada (SkIN Canada) | An-Wen Chan | Sarah Hedtrich as one of ≥ 20 Canadian clinicians and researchers |
Thrasher Research Institute | A drug delivery technology for activating the tumor immune microenvironment of peritoneal metastases | Anil Maharaj | Watt (University of Utah), Cohen-Wolkowiez (Duke University) |
Genome Canada | DNA sequencing platform | Marra | Corey Nislow |
Canadian Found. Innovation | DNA sequencing sample preparation | Corey Nislow | Farrer |
Genome BC | Community pharmacy sequencing | Corey Nislow | DesRosier |
GENETIC NETWORKS, LLC | Drug screening | Guri Giaever | Corey Nislow |
NASA | Cellular response to microgravity | Guri Giaever | Corey Nislow |
Brain Canada, Team Grant | Biomarkers spinal cord injury | Kwon | Corey Nislow |
Canada Research Chair | Canada Research Chair Tier 1 | Corey Nislow | |
Canadian Found. Innovation | Human exomics | Corey Nislow | |
Genome BC | Community pharmacy sequencing | Corey Nislow | DesRosier |
MITACS | Yeast Strain Development | Corey Nislow, Guri Giaever | Renaissance BioSciences |
Heart and Stroke Foundation of Canada (HSFC) | Role of cardiac lipoprotein lipase in diabetic heart disease | Brian Rodrigues | |
CIHR | Endothelial heparanase regulation of cardiac metabolism | Brian Rodrigues | |
CIHR | Role of cardiac lipoprotein lipase in diabetic heart disease | Brian Rodrigues | |
UBC Research Excellence Cluster Funding | BC Diabetes Research Network Established Cluster | Bruce Verchere | Brian Rodrigues |
National Centres of Excellence | Development and utilization of in vivo systems to optimize lipid nanoparticles for therapeutic genome editing: Focus on delivery to muscle for the treatment of LPL Deficiency | Colin Ross | Shyh-Dar Li, Sarah Hedtrich |
CIHR | Characterizing and validating diacetylspermine as a metabolic biomarker of drug response and precision treatment in triple-negative breast cancer | Thomas Velenosi | Karen Gelmon |
CIHR | Development and evaluation of novel nanoparticle formulations for therapeutic genome editing | Colin Ross | Thomas Velenosi, Anna Blakney, Pieter Cullis, Graham Dellaire, Urs Hafeli, Sarah Hedtrich, Ujendra Kumar, Shyh-Dar, Li, Brian Rodrigues, Ramona Salvarinova |
CIHR | The role of the tumor microenvironment in regulating metastatic growth | Karla Williams | |
CIHR | Extracellular vesicle detection methods and probe development | Algar, R, Karla Williams | |
NSERC | Extracellular vesicles biogenesis and function | Karla Williams | |
GlycoNet | Extracellular vesicle associated glycans as a novel platform for breast cancer detection | Karla Williams | Mahal, L (UofA) and Watson, P (BC Cancer) |
Susan G. Komen | Targeting breast cancer dissemination and developing novel prognostic methods | Karla Williams | |
NMIN Initiatives Project | Immunotherapy of inoperable and locally advanced hepatocellular carcinoma | Shyh-Dar Li | Collaborator: Karla Williams, David Liu; Yunching Chen; Gregor Reid; Wu-Chou Su, Li-Chun Lu |
Andira Pharmaceuticals | Anti-metastatic drug testing using the chick embryo model | Karla Williams | |
Cancer Research Society - Operating Grant | Development of a Liquid Biopsy for Early Breast Cancer Detection | Karla Williams | Peter Watson |
GlycoNet Team Grant | Development of antagonists targeting immunomodulatory Siglecs | Matthew Macauley | Karla Williams, Ratmir Derda |
Womens Health Research Institute Catalyst Grant | Extracellular vesicle loading of siRNA p53 lipoplexes for the treatment of triple negative breast cancer | Nikki Salmond | Karla Williams, Shyh-Dar Li |
CIHR Project Grant | Overcoming DHFR Inhibitor Resistance in Cancer | Brent Page | Karla Williams, Adam Frankel |
CIHR Project Grant | Influence of breast cancer-derived extracellular vesicles on lung metastasis of triple negative breast cancer | Alison Allan (UWO) | Karla Williams, David Litchfield |
CIHR Project Grant | Materials and technologies for highly sensitive biomarker analysis of extracellular vesicles toward cancer diagnostics | Karla Williams, Russ Algar | |
CIHR Project Grant | Characterization of invadopodia formation in response to local cues and their role in orchestrating metastasis | Karla Williams | |
NSERC Discovery Grant | Extracellular vesicles: biogenesis, composition, and biological function | Karla Williams | |
Susan G. Komen | Targeting breast cancer dissemination and developing novel prognostic methods | Karla Williams | |
NSERC | Biochemical and Cellular Characterization of Dyskerin Functions | Judy Wong | |
CRS | Tumor-Specific Targeting of Telomere with Combination Therapeutics | Judy Wong | |
University of Pennsylvania Orphan Disease Centre | Characterization of Telomere Maintenance in Tumor Models of Dyskeratosis Congenita | Judy Wong | |
CIHR | Identification of therapeutically relevant targets in telomerase overexpressing prostate cancers | Franco Vizeacoumar | Andrew Freyward, Yuzhou Wang, Judy Wong |
Natural Sciences and Engineering Research Council | Structure-Function Relationship Study of Telomerase Reverse Transcriptase's Non-Canonical Activities | Judy Wong | |
CIHR | Molecular and Functional Genomic Characterization of G-quadruplexes in Cancer with the Alternate Lengthening of Telomere (ALT) Mechanism | Judy Wong | Peter Stirling |
CIHR | Identification of therapeutically relevant targets in telomerase overexpressing prostate cancers | Franco Vizeacoumar and Andrew Freyward | Judy Wong |
CRS | Applying Synthetic Dosage Lethality to Develop Therapeutic Strategies for Ovarian Clear Cell Carcinoma | Franco Vizeacoumar and Andrew Freyward | Judy Wong |
NSERC | Structure-Function Relationship Study of Telomerase Reverse Transcriptase's Non-Canonical Activities | Judy Wong |