Active Grants

Granting AgencySubjectPrincipal InvestigatorCo-Investigator(s)
Canadian Institutes of Health Research (CIHR)DRUG SAFETY and EFFECTIVENESS NETWORK (DSEN) SEARCH (active Surveillance and Evaluation of Adverse Reactions in Canadian Healthcare) & PREVENT (Pharmacogenomics of Adverse Reaction EVEnts) National TeamColin RossAbby Collier, Bruce Carleton, Amit Bhavsar, M Rogers, Rod Rassekh, Michael Rieder, Shinya Ito
Office of the Vice President Research and Innovation, UBCResearch Support for the Pharmaceutical Sciences Analytical SuiteAbby CollierJudy Wong
Faculty of Pharm Sci Office of Associate Dean Research Improved PBPK Scaling from Preclinical Models to First-in-Human Trials. Funds for Re-opening after COVIDAbby Collier 
National Science and Engineering Council of Canada (NSERC)A UHPLC for steroid analysis
Research Tools and Infrastructure competition
Abby Collier, Kiran SomaKiran Soma
CIHRValidation and commercialization of an innovative analgesic for chronic pain
Project Grant
Shyh-Dar LiAbby Collier, Brian Cairns, Jim Kim, Amanda Malone, Ernie Puil
Genentech LtdImproved PBPK Scaling from Preclinical Models to First-in-Human TrialsAbby Collier 
CIHRDRUG SAFETY and EFFECTIVENESS NETWORK (DSEN) SEARCH (active Surveillance and Evaluation of Adverse Reactions in Canadian Healthcare) & PREVENT (Pharmacogenomics of Adverse Reaction EVEnts) National TeamColin RossAbby, Collier, Bruce Carleton, Ursula Amstutz, Amit Bhavsar, Kerry Goralski, Greg Guilcher, Shinya Ito, Denis Lebel, Rod Rassekh, Michael Rieder, Geert t’Jong, Regis Vaillancourt
NSERCPost Translational Mechanisms of UGT Function
Discovery Grant
Abby Collier 
CIHRCorrecting monogenic skin diseases in situ: Assessing the potential of topically applicable gene therapiesSarah HedtrichShyh-Dar Li, Colin Ross
Canada Foundation for Innovation and BC Knowledge Development FundComplex human-based organ (disease) models for basic and preclinical research with a focus on human epitheliaSarah Hedtrich 
NSERCDevelopment of complex human-based organ modelsSarah Hedtrich 
BREATHE The Lung FoundationThe Skin-Lung Crosstalk: Approaching the Atopic MarchSarah HedtrichTillie Hackett
CIHRTargeting TSLP - Novel anti-inflammatory compounds for the treatment and prevention of atopic diseasesSarah HedtrichBrent Page, David Granville
MitacsRational Nanoparticle Design for Efficient Transmucosal Gene DeliverySarah Hedtrich & James Feng (Math, UBC) 
Federal Ministry of Education and Research, GermanyImmuSkin - Autologous approach for the development of an immunocompetent skin modelSarah Hedtrich & Burkhard Kleuser (U Potsdam, Germany) 
National Centres of ExcellenceNanoparticle formulations for anti-inflammatory IDR peptidesBob HancockSarah Hedtrich, Andrew Halayko, Neelofer Mookherjee, Azita Haddadi
CIHR Catalyst GrantSkin Investigation Network of Canada (SkIN Canada)An-Wen ChanSarah Hedtrich as one of ≥ 20 Canadian clinicians and researchers
Thrasher Research InstituteA drug delivery technology for activating the tumor immune microenvironment of peritoneal metastasesAnil MaharajWatt (University of Utah), Cohen-Wolkowiez (Duke University) 
Genome CanadaDNA sequencing platformMarraCorey Nislow
Canadian Found. InnovationDNA sequencing sample preparationCorey NislowFarrer
Genome BCCommunity pharmacy sequencingCorey NislowDesRosier
GENETIC NETWORKS, LLC Drug screeningGuri GiaeverCorey Nislow
NASACellular response to microgravityGuri GiaeverCorey Nislow
Brain Canada, Team GrantBiomarkers spinal cord injuryKwonCorey Nislow
Canada Research ChairCanada Research Chair Tier 1Corey Nislow 
Canadian Found. InnovationHuman exomicsCorey Nislow 
Genome BCCommunity pharmacy sequencingCorey NislowDesRosier
MITACSYeast Strain DevelopmentCorey Nislow, Guri GiaeverRenaissance BioSciences
Heart and Stroke Foundation of Canada (HSFC)Role of cardiac lipoprotein lipase in diabetic heart diseaseBrian Rodrigues 
CIHREndothelial heparanase regulation of cardiac metabolismBrian Rodrigues 
CIHRRole of cardiac lipoprotein lipase in diabetic heart diseaseBrian Rodrigues 
UBC Research Excellence Cluster FundingBC Diabetes Research Network Established ClusterBruce VerchereBrian Rodrigues
National Centres of ExcellenceDevelopment and utilization of in vivo systems to optimize lipid nanoparticles for therapeutic genome editing: Focus on delivery to muscle for the treatment of LPL DeficiencyColin RossShyh-Dar Li, Sarah Hedtrich
CIHRCharacterizing and validating diacetylspermine as a metabolic biomarker of drug response and precision treatment in triple-negative breast cancer Thomas VelenosiKaren Gelmon
CIHRDevelopment and evaluation of novel nanoparticle formulations for therapeutic genome editingColin RossThomas Velenosi, Anna Blakney, Pieter Cullis, Graham Dellaire, Urs Hafeli, Sarah Hedtrich, Ujendra Kumar, Shyh-Dar, Li, Brian Rodrigues, Ramona Salvarinova
CIHRThe role of the tumor microenvironment in regulating metastatic growthKarla Williams 
CIHRExtracellular vesicle detection methods and probe developmentAlgar, R, Karla Williams 
NSERCExtracellular vesicles biogenesis and functionKarla Williams 
GlycoNetExtracellular vesicle associated glycans as a novel platform for breast cancer detectionKarla WilliamsMahal, L (UofA) and Watson, P (BC Cancer)
Susan G. KomenTargeting breast cancer dissemination and developing novel prognostic methodsKarla Williams 
NMIN Initiatives ProjectImmunotherapy of inoperable and locally advanced hepatocellular carcinomaShyh-Dar LiCollaborator: Karla Williams, David Liu; Yunching Chen; Gregor Reid; Wu-Chou Su, Li-Chun Lu
Andira PharmaceuticalsAnti-metastatic drug testing using the chick embryo modelKarla Williams 
Cancer Research Society - Operating GrantDevelopment of a Liquid Biopsy for Early Breast Cancer DetectionKarla WilliamsPeter Watson
GlycoNet Team GrantDevelopment of antagonists targeting immunomodulatory SiglecsMatthew MacauleyKarla Williams, Ratmir Derda
Womens Health Research Institute Catalyst GrantExtracellular vesicle loading of siRNA p53 lipoplexes for the treatment of triple negative breast cancerNikki SalmondKarla Williams, Shyh-Dar Li
CIHR Project GrantOvercoming DHFR Inhibitor Resistance in CancerBrent PageKarla Williams, Adam Frankel
CIHR Project GrantInfluence of breast cancer-derived extracellular vesicles on lung metastasis of triple negative breast cancerAlison Allan (UWO)Karla Williams, David Litchfield
CIHR Project GrantMaterials and technologies for highly sensitive biomarker analysis of extracellular vesicles toward cancer diagnosticsKarla Williams, Russ Algar 
CIHR Project GrantCharacterization of invadopodia formation in response to local cues and their role in orchestrating metastasis Karla Williams 
NSERC Discovery GrantExtracellular vesicles: biogenesis, composition, and biological functionKarla Williams 
Susan G. KomenTargeting breast cancer dissemination and developing novel prognostic methodsKarla Williams 
NSERCBiochemical and Cellular Characterization of Dyskerin FunctionsJudy Wong 
CRSTumor-Specific Targeting of Telomere with Combination TherapeuticsJudy Wong 
University of Pennsylvania Orphan Disease CentreCharacterization of Telomere Maintenance in Tumor Models of Dyskeratosis CongenitaJudy Wong 
CIHRIdentification of therapeutically relevant targets in telomerase overexpressing prostate cancersFranco VizeacoumarAndrew Freyward, Yuzhou Wang, Judy Wong
Natural Sciences and Engineering Research CouncilStructure-Function Relationship Study of Telomerase Reverse Transcriptase's Non-Canonical ActivitiesJudy Wong 
CIHRMolecular and Functional Genomic Characterization of G-quadruplexes in Cancer with the Alternate Lengthening of Telomere (ALT) MechanismJudy WongPeter Stirling
CIHRIdentification of therapeutically relevant targets in telomerase overexpressing prostate cancersFranco Vizeacoumar and Andrew FreywardJudy Wong
CRSApplying Synthetic Dosage Lethality to Develop Therapeutic Strategies for Ovarian Clear Cell CarcinomaFranco Vizeacoumar and Andrew FreywardJudy Wong
NSERCStructure-Function Relationship Study of Telomerase Reverse Transcriptase's Non-Canonical ActivitiesJudy Wong 

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