Shyh-Dar Li PhD

Professor

Profile Type
Faculty
Accepting Graduate Students
Yes
About

Dr. Shyh-Dar Li received his BSc in pharmacy from National Taiwan University in 1998 and PhD in pharmaceutical sciences from the University of North Carolina at Chapel Hill in 2008. He finished his postdoctoral training at Moores Cancer Center at the University of California, San Diego in 2009. He is now the Tong Louie Chair Professor in Pharmaceutical Sciences and the Chair of Nanomedicine and Chemical Biology at UBC Faculty of Pharmaceutical Sciences.

Dr. Li has won several international and national research awards, including 2014 AFPC New Investigator Award, 2013 AAPS New Investigator Award in Pharmaceutics and Pharmaceutical Technologies, 2013 CIHR New Investigator Award, 2013 CSPS Early Career Award, and 2012 Prostate Cancer Foundation Young Investigator Award. 

Dr. Li's research focuses on developing innovative drug delivery systems to enable novel therapies with biological drugs including peptides, proteins, antibodies, and nucleic acids. His research program has been supported by CIHR, NSERC, and MITACS.

Publications

Resiquimod-loaded cationic liposomes cure mice with peritoneal carcinomatosis and induce specific anti-tumor immunity. Chao PH, Chan V, Wu J, Andrew LJ, Li SD. J Control Release. 2024;372:362-371. doi: 10.1016/j.jconrel.2024.06.041.

Intranasal delivery of low-dose anti-CD124 antibody enhances treatment of chronic rhinosinusitis with nasal polyps. Wu J, Jones N, Chao PH, Chan V, Hohenwarter L, Wu A, Bergamo M, Rodríguez-Rodríguez C, Saatchi K, Liang A, Häfeli UO, Tan Z, Hedtrich S, Andrew LJ, Li SD. Biomaterials. 2024;308:122567. doi: 10.1016/j.biomaterials.2024.122567. 

Systemic delivery of proteins using novel peptides via the sublingual route. Wu J, Jones N, Hohenwarter L, Zhao F, Chan V, Tan Z, Carlaw T, Morin T, Li J, Kaur T, Andrew LJ, Ross CJD, Hedtrich S, Li SD. J Control Release. 2024;368:290–302. doi: 10.1016/j.jconrel.2024.02.042.

A Novel Leu-Enkephalin Prodrug Produces Pain-Relieving and Antidepressant Effects. Hohenwarter L, Puil E, Rouhollahi E, Bohrmann L, Lu S, Saatchi K, Häfeli UO, Barr A, Böttger R, Viswanadham KKD, Li SD. Mol Pharm. 2024;21(2):688–703. doi: 10.1021/acs.molpharmaceut.3c00807.

For complete publications and recent updates, please visit https://pubmed.ncbi.nlm.nih.gov/?term=li+shyh-dar&sort=date.


Contact Details

604-827-0675

shyh-dar.li@ubc.ca

Office 5519, Pharmaceutical Sciences Building


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